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I was diagnosed with type 2 diabetes about 3 years ago. I have tried several medications since then, but currently I'm on Actos and I see very good results. My glucose numbers are low enough, and so far I have experienced no side effects at all.
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The publishes a study linking thiazolidinedones, specifically Actos and Avandia, to diabetic macular edema, a condition that causes swelling in the eye.
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It helps the body become more sensitive to the insulin it produces.
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Based on the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III criteria and the 2004 ATP III Guidelines update.
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ACTOS is a diabetes medicine called pioglitazone that may be taken alone or with other diabetes medicines.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
They can either be used alone or with another medication.
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USES: Glipizide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes.
People with severe congestive heart failure shouldn't use Actos.
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Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses.
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Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
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Since the early 1990s, Actos has been wreaking havoc on the health of the diabetic patients that it was prescribed to in the form of damage to liver and kidneys, heart attacks, blindness and even bladder cancer.
You should contact your doctor immediately if you have any rare but serious side effects, including changes in vision, bone fractures, frequent or painful urination, dark or reddish-colored urine, jaundice, stomach pain, or persistent nausea and vomiting.
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Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD.
The manufacturers were found to have known about Actos risks, including cancer of the bladder, yet failed to issue adequate warnings to inform the medical and public communities of these potential complications.
See also: What other drugs will affect Actos?
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Use Panax ginseng with caution if you have heart disease.
For patients who had not been previously treated with antidiabetic medication (24%), mean values at screening were 10.
If you are already taking another anti-diabetic drug (such as chlorpropamide), follow your doctor's directions carefully for stopping the old drug and starting glipizide.
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However, certain Actos side effects are more serious and should be reported to your healthcare provider, including trouble breathing, low blood sugar, rapid weight gain, and vision changes.
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In fact, an FDA Safety Accouncement involving the links between bladder cancer and Actos, including Acto plusmet with metformin, for more than one year, may experience an increased risk for developing the deadly cancer.
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The study looked at a half-million side effect reports associated with various diabetes medications and found that one-fifth of those involving bladder cancer occurred in patients using Actos.
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FDA is also aware of a retrospective cohort study using data from the French National Health Insurance Plan.
Researchers found that significantly fewer women given Zofran suffered a spontaneous abortion, compared to women who did not take the drug, and there were no statistically significant differences in the rates of major birth defects, stillbirth, preterm delivery or delivery of a low-birth-weight infant, the findings indicate.
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You should not take Actos if you are being treated for bladder cancer.
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Do not breast-feed while you are taking pioglitazone.
In one study, the use of rosiglitazone decreased the risk of diabetes in adults with impaired glucose tolerance by 62%; given concerns about cardiovascular safety, however, the Food and Drug Administration has restricted the use of rosiglitazone therapy to patients in whom glycemic control cannot be achieved with other medications and who cannot take pioglitazone.
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If caught before it spreads, the cancer can usually be treated.
All Actos cases are being pursued under a contingency fee, which means that there are unless a recovery is obtained.
The observational data further suggest that the risk increases with duration of use.
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It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.
Patients who experience an unusually rapid increase in weight or edema or who develop shortness of breath or other symptoms of heart failure while on Actos should immediately report these symptoms to a physician.
Researchers in Europe, Canada, and the United States have warned of studies showing an increased risk for bladder cancer among patients who took Actos for more than a year.
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Visit your doctor or health care professional for regular checks on your progress.
If your cancer can be directly tied to the drug, then you can likely file against the manufacturer (and possibly its US distributor).
The risk of fracture should be considered in the care of patients, especially female patients, treated with pioglitazone and attention should be given to assessing and maintaining bone health according to current standards of care.
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However, not all defective products are removed before they cause harm.
If you notice other side effects that you think are caused by this medicine, tell your doctor.
ACTOS exerts its antihyperglycemic effect only in the presence of insulin.
The statute of limitations for wrongful death cases varies from one to three years depending on the state, and your attorney will need time to gather evidence and file the appropriate paperwork before this deadline lapses.
The French government has completely pulled Actos off their shelves, while the German government has recently advised all doctors to cease prescribing Actos until further studies can be completed.
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These include cold or allergy medications, sleeping pills, narcotic pain medications, medications for seizures, muscle relaxers, and other medications for depression and anxiety.
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PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor.
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Provide contact information below and additional private comments if you want an attorney to contact you to review a potential case.
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