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Intermediate" indicates that inhibitory concentrations of the antibiotic may be achieved if high dosage is used or if the infection is confined to tissues or fluids in which high antibiotic concentrations are attained.
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Cultivation of Borrelia burgdorferi from joint fluid three months after treatment of facial palsy due to Lyme borreliosis.
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Susceptible” indicates that the antimicrobial drug is likely to inhibit growth of the microorganism if the antimicrobial drug reaches the concentration usually achievable at the site of infection.
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Whether to close a wound resulting from a cat or dog bite is the subject of debate.
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The highest reported incidence of Lyme disease occurs among children 5 - 14 years old and adults 45 - 54 years old.
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However, the most rapid and evident effect of antibiotic treatment will be on the composition of normal microflora because antibiotic treatment will select for resistant variants not only in the treated virulent microorganisms, but in the commensal microflora also (see below).
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